Clinical Test Expectation PGE-1 – Human Subjects : Vasoldilator used for treatment for erectile dysfunction.
Strength – 2MG per vial
Prostaglandin E1 (PGE1) is an endogenous prostaglandin synthesized from linolenic acid. PGE1 is clinically used for its vasodilatory activity as a treatment for erectile dysfunction. PGE1 also exhibits nephroprotective and pro-angiogenic activities. PGE1 decreases small intestine mucosa lesions in animal models of intestinal ischemia/reperfusion. PGE1 also improves renal function in subject with renal dysfunction or renal failure. Additionally, PGE1 enhances VEGF production in animal models of ischemia.
In the treatment of erectile dysfunction, prostaglandin E1 (PGE1) works by increasing cAMP production, reducing the influx of calcium within the penile vascular smooth muscle. The result is a relaxation of trabecular smooth muscle by arterial dilation. Blood becomes entrapped in the penis, which eventually leads to an erection.
PGE1 can also serve as a treatment for maintaining the patency of ductus arteriosus heart defects in neonates by a similar mechanism. PGE1 dilates the ductus smooth muscle so that it remains open and blood flow may be maintained. Ductal patency allows for oxygenated blood flow until the congenital anomaly can be surgically corrected.
Dosing Details – PGE-1
Please consult medical professional for dosing information.
How long will a vial last ?
A vial should last 10 days.